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Science 302 , 826830 (2003)

Additionally, CD38 expression on MM cells decreases rapidly during daratumumab treatment, is markedly reduced at time of progression, and may take up to 6 months to rebound after stopping daratumumab [35]

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Key differences in needle sizes and injection depths: Subcutaneous: Shorter needles (1/2 to 5/8 inch), shallow injection depth Intramuscular: Longer needles (1 to 1.5 inches), deeper injection depth Research on Effectiveness and Absorption Rates Studies show both methods can be effective for HCG