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however, one observational study suggests better efficacy with cyanocobalamin than with methylcobalamin

Nature 567 , 257261 (2019)

Changes of energy metabolism in failing heart and its regulation by SIRT3

It's noteworthy that these Parkinson-like events following ranibizumab administration are distinguished by the absence of cortical and subcortical atrophy, suggesting a unique pathophysiological mechanism distinct from typical PD presentations (Sultana and Scondotto 2020)