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Remarkably, in the non-operated rats, the adaptive response does not affect the amino acid ratios, confirming the maintenance of the normal metabolic state in the thiamine-exposed cerebral cortex, despite the homeostatic decreases in the amino acid levels

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10.1002/mnfr.201800079 123

Bowers E, Entrup GP, Islam M, Mohan R , Lerner A, Mancuso P, Moore BB, Singer K