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Blood disorders Anemia, increased white blood cell count, platelets, decreased white blood cell counts, decreased neutrophils, decreased lymphocytes, decreased platelets, reductions in CD4 helper lymphocytes, reductions in CD8 positive suppressor lymphocytes, reductions or excesses of IgA, IgG, IgM, IgE, a known condition called MGUS, myelodysplastic syndrome (reduced red cells, white cells, platelets), and increased MCV (mean corpuscular volume)

Fertil Steril 93, 112 (2010)

PNFs are benign nerve sheath tumours that occur in ~40% of NF1 patients

Disruptions in the metabolism and function of key CEAAs, particularly Asn, Gly, Glu, Asp, and Gln, as well as Cys, underscore their roles in maintaining epithelial barrier integrity, modulating immune responses, regulating oxidative stress, and supporting gut microbiota balance