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The Wells score is determined by major risk factors (recent history of surgery or bed rest, immobilization, or presence of cancer), physical exam findings (edema, engorgement, enlargement, tenderness, and superficial vein dilation in the affected limb), and history (previous DVT and absence of another likely explanation for signs and symptoms)

PlexusDx maps 14 pathways and 150+ genetic insights including FTO rs9939609 (metabolic edema risk), MC4R rs17782313 (sodium-retention predisposition), and inflammatory markers that directly influence how quickly and completely you'll experience edema resolution

Cortisol is a potent anti-inflammatory agent that reduces swelling, alleviates pain, and promotes healing

GH pulses lead to hepatic IGF-1 secretion, which stimulates myogenesis and hypertrophy, particularly under resistance training conditions. Thorner et al., Nature Reviews Endocrinology 5