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Benkhoucha M, Santiago-Raber M-L, Schneiter G, Chofflon M, Funakoshi H, Nakamura T, et al

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Because there are no vegetable sources of vitamin B12, strict vegans must supplement, consume fortified foods, or receive regular Vitamin B12 injections to avoid serious health consequences

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Approach Phase 2b trial arm Duration 24 weeks Review Point Week 12 and 24 Notes METAOD006 (OPTIONS) used 24 weeks at oral doses 0.25, 0.5, or 1 mg/day in 502 obese adults

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