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Rapid hepatobiliary excretion of micelle-encapsulated/radiolabeled upconverting nanoparticles as an integrated form

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In the case of L-EGCG-Mn, a flavonoid preparation that is both pH-responsive and MRI-imaging, the chelation of Mn 2+ by EGCG is greatly reduced in acidic environments, which prompts its release for MRI capability [165]

Furthermore, in a chronic social defeat stress mouse model of depression, inhibiting intestinal T cells with TCR and antibodies could directly prevent stress-induced T-cell accumulation in the meninges and subsequent behavioral deficits [337]