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First, using a parallel approach to our human study, we applied 1 H-MRS at ultra-high field (9.4T) to measure rats GSH content in the NuAc (Figure 2a-c) and divided animals as either High or Low-GSH (i.e., H-GSH and L-GSH) following a median split, following procedures in our human study (Figure 2d)

T., Smith-Ryan, A

Juvenile Animal Toxicology In studies of valproate in immature animals, toxic effects not observed in adult animals included retinal dysplasia in rats treated during the neonatal period (from postnatal day 4) and nephrotoxicity in rats treated during the neonatal and juvenile (from postnatal day 14) periods

Acting as the pro-drug of salsolinol, alcohol excites DA neurons in the posterior ventral tegmental area (pVTA) and increases DA release in the nucleus accumbens shell (AcbSh)