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8 Therapeutic role of AST in MS Multiple sclerosis is a neurodegenerative disorder where the bodys immune system works against the myelin sheath in the central nervous system, causing nerve damage and disrupting signal transmission

[121] Age is also a contributing factor: elderly individuals are often achlorhydric due to reduced parietal cell function in the stomach, increasing their risk of vitamin B 12 deficiency

This is why its often recommended to separate oral high-dose vitamin C from B12 supplements by several hours

However, further studies are required to determine the safety, further efficacy, side effects, and dosage of the extract or isolated phytochemical flavone