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Subsequently, GSH is synthesized under the catalysis of glutamate cysteine ligase (GCL) and glutathione synthetase (GSS), and finally, GPX4 dependent on GSH converts PLOOH into non-toxic lipophilic alcohols [38]

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Apoptosis, pyroptosis, and ferroptosis conspiringly induce immunosuppressive hepatocellular carcinoma microenvironment and gammadelta T-cell imbalance