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doi: 10.23750/abm.v89i9-S.7960 37 JungGHernandez-IllanEMoreiraLBalaguerFGoelA

Acute use of this drug in animal models has been seen to reverse several characteristics of senescent fibroblasts,84 protect against UV radiation damage,85 and reinitiate fibroblast proliferation.84 Metformin has also shown senomorphic effects in lung fibroblasts.86 Flavonoids and plant extracts such as Solidago virgaurea extracts, are capable of modulating cellular senescence.82 Senolytics and senomorphics are promising new agents in the field of human aging, but clinical studies are needed to evaluate their true effectiveness and safety

In the following section, we review the pharmacologic approaches that have been trialed in impulsivity (Table 4)

In such cases, surgical removal of excess tissue from the palate may be necessary