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Improved tendon health or ligament health

For instance, it is utilized by your body in synthesizing DNA and producing new red blood cells, in addition to generating energy

A 2025 systematic review and meta-analysis in Frontiers in Pharmacology (Mazur and colleagues, 16 studies, 6,098 participants) found that oral, sublingual, and intramuscular B12 all raised serum cobalamin to a comparable degree, with no statistically significant difference between routes

Notably, studies have shown that knocking down NNMT in adipose tissues and livers of mice fed a high-fat diet resulted in decreased serum TG and FFA levels (Kraus et al., 2014)