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Both approaches complement each other

10.1016/j.abb.2019.108121 65 RebernikM.LenariB.NovinecM

376 In human lung adenocarcinoma, TP53 mutation has been suggested to serve as a potential predictor of a good response to checkpoint inhibitors targeting PD-L1 because missense mutations in TP53 correlate positively with elevated PD-L1 expression