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The expression of p53, MDM2 and Ref1 gene in cultured retina neurons of SD rats treated with vitamin B1 and/or elevated pressure

When long term stress occurs, unlike other physiologic functions (homeostatic), the stress response often stays up-regulated even after the stressful situation is resolved

Doru, S., Yaar, E

In undifferentiated keratinocytes, VDR primarily regulates downstream target genes through interactions with the mediator (MED) complex [124].In more differentiated keratinocytes, VDR function is predominantly mediated via coactivators of the steroid receptor coactivator (SRC) family, particularly SRC2 and SRC3 [125]