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(3) For a biosimilar biological product (as defined in 414.902) (i) In circumstances in which negative or zero manufacturer's ASP data is reported for one or more, but not all, NDCs for a given quarter, the payment limit for the given quarter is calculated using only NDCs with positive manufacturer's ASP data

Aluminum salts are commonly used adjuvants that have been associated with a variety of local adverse reactions including granuloma formation, allergic reaction, and myofasciitis

Levels of methylmalonic acid (MMA) and homocysteine rise, because the body needs B12 to convert them into other compounds