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This peptide also appeared to modulate immune cell behavior, with reports of increased macrophage activity, which may support resolution rather than persistence of inflammation

Regular monitoring of Vitamin B12 levels may be necessary to adjust the dosage and to assess the effectiveness of the treatment

Endothelial dysfunction, including decreased endothelial cell-dependent vasorelaxation, is increasingly proposed to be triggered by free radicals generated during auto-oxidation of homocysteine (Loscalzo, 1996)