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FIGURE 5 Hypoxia-Inducible Factor-3 mRNA Expression was Significantly Increased in Alzheimers Disease and Parkinsons Disease Due to the fact that T2D and neurodegeneration disease shared the overlapping pathophysiological mechanisms and pathways, we detected Mmp8 and Hif3 mRNA expression value in AD and PD samples by analyzing gene expression datasets in GEO