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To clarify how integrated safety data operates in practice, the following areas are addressed: Clinical safety monitoring during development Pharmacovigilance Adverse Event Assessment Post-approval safety oversight and signal detection Regulatory documentation and data traceability Clinical Safety Monitoring During Drug Development Clinical teams monitor safety data continuously during trials to detect emerging risks early

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These are really reactive & lead to the production of hydrogen peroxide (HO) which is one of those ROS that glutathione is needed to neutralize

However, we cannot assume that all CAT enzymes localised to various subcellular regions are functionally active