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The two latter groups are represented by the SLC13 and SLC26 gene families, respectively, (Takahashi et al., 2011a)

Additional preclinical safety evaluation and regulatory toxicology research may help clarify how findings observed in experimental models translate to human biology

Similarly, copper exposure in mouse microglial cells triggers an inflammatory response, resulting in the upregulation of NLRP3/caspase 1/GSDMD axis proteins and subsequent pyroptosis