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[11] [12] [81] Tamoxifen binds to ER competitively (with respect to the endogenous agonist estrogen) in tumor cells and other tissue targets, producing a nuclear complex that decreases DNA synthesis and inhibits estrogen effects

Ocular imaging Eye fundus imaging (MICRON IV, Phoenix, USA) and optical coherence tomography (Bioptigen OCT system, Leica microsystems, Germany) were performed at 7 and 15 days post-implantation (dpi) for all rats to monitor inflammation and confirm correct implantation

Body composition trends shifted favorably over months four to six

The right schedule may depend on the reason for use, health history, product formulation, route of administration, and tolerability