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So far, natural chalcones isoliquiritigenin (2,4,4-trihydroxychalcone) and glabrene from licorice roots 283 , 2,4,2',4'-hydroxycalcone and three of its analogs with 3'-substituted resorcinol moieties from Morus australis (Figure 6, 19 22 ) 291 , 2,4,2',4'-tetrahydroxy-3-(3-methyl-2-butenyl)-chalcone from Morus nigra 292 , vulpinoideol B from Carex vulpinoidea seeds 293 , dihydrochalcones from Flemingia philippinensis 210 , 2,4,2,4-tetrahydroxychalcone (IC 50 = 0.07 0.02 M) and morachalcone A (IC 50 = 0.08 0.02 M) from Morus alba L

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15,16 BPPV is most commonly caused by displaced particles of calcium debris (called canaliths) in the small canals of the inner ear