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Second, observed reductions in LDL-C and PCSK9 were durable up to two years after dosing, with additional follow-up ongoing, consistent with a potential permanent treatment effect resulting from DNA modification

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1.1 Neonicotinoids The age of neonicotinoids (neonics) began with nitromethylene nithiazine, but really was inspired by Shinzo Kagabus important discoveries (Nugnes et al., 2023)