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Telitacicept, a transmembrane activator and cyclophilin ligand interactor (TACI)-Fc fusion protein, has shown significant clinical effects in the treatment of immunoglobulin A nephropathy (IgAN) as demonstrated in a phase II randomized placebo-controlled trial

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In brief, all levels of cervical and lumbar DRGs were dissected and digested in a mixture of papain/collagenase/dispase and triturated using glass Pasteur pipettes

Its usually temporary and can be managed by increasing magnesium or potassium intake