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Opiates such as morphine reliably inhibit the behavioral, electrophysiological and biochemical responses evoked by acute thermal, mechanical and other noxious stimuli in rats

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In addition to participating in ubiquitin-dependent mitophagy, some mitochondrial proteins also act as mitophagy receptors, directly mediating the targeted binding and degradation process of dysfunctional mitochondria to autophagosomes (Figure 2f) (Table 1)