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Description

CIRI: Cerebral ischemia reperfusion injury

Together with naringin, the use of poncirin from Poncirus trifoliata extract seems to exert antidepressant effects in mice by restoring vascular endothelial cell integrity in the hippocampus and controlling the neuroinflammatory responses of microglia at the Cornu Ammonis 1 (CA1) and dentate gyrus (DG) regions of the hippocampus [178]