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Overexpression of malate synthase from the natural oxalate-resistant A

Furthermore, directed differentiation protocols allow for modeling specific brain regions [159, 160]

B-12 injections can be beneficial for individuals who have difficulty absorbing B-12 from their diet or supplements, including those with pernicious anemia, certain gastrointestinal conditions, and older adults whose B-12 absorption decreases with age

Together, these data support a temporal model in which mitochondrial stress and iron abnormalities appear early, intensify at the mid-stage and culminate in overt ferroptosis with structural failure in late-stage IDD