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Excessively high intake of certain B-vitamins can also cause headaches: Vitamin B6 (Pyridoxine): High doses of vitamin B6 can lead to neurological issues, including headaches, sensory neuropathy, and other symptoms such as numbness and tingling in the extremities

The microneedling evidence is anchored by Dhurat et al.s 2013 RCT showing 82% patient response rate