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Research has also examined its potential roles in modulating gene expression associated with extracellular matrix remodelling

Customized protocols may combine topical and injectable GHK-Cu delivery methods with complementary treatments such as platelet-rich plasma , microneedling , prescription medication( such as Minoxidil) , and nutritional optimization

Simultaneously, GHK-Cu appears to support matrix metalloproteinases (MMPs) and their inhibitors (TIMPs), suggesting it might regulate both synthesis and degradation of ECM componentsan important attribute for dynamic tissue remodeling

GHK-Cu increased collagen synthesis 9-fold in healthy tissue while improving epithelialization and activating key cell populations involved in repair