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It has been shown that ADC mainly acts on the Nrf2-AREs pathway and scavenges free radicals to exert an ferroptosis inhibitory effect, and ADC may interfere with the Keap1-Nrf2 pathway and activate the Nrf2-AREs pathway (Tan et al., 2021)

As we age or face environmental stressors, glutathione levels can decline, making supplementation increasingly important for many individuals

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The study by Zou et al (146) identified eight key ferroptosis-related genes and ferroptosis signatures through the Gene Expression Omnibus ( database