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However, an important disadvantage of AMB is its high cytotoxicity, which may produce serious kidney and liver failure (Laniado-Laborin and Cabrales-Vargas, 3-bromopyruvate (3BP), a structural analog of a key cellular metabolite (pyruvate) is one of the most widely studied compounds from the group of halogenated carboxylic acids

Research in the Gilkes Lab is funded by The Jayne Koskinas Ted Giovanis Foundation for Health and Policy and the NCI/SKCCC Core grant number P50CA006973 (D.G.)

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