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Furthermore, aging involves biological and physiological changes that can affect the sensation of neuropathic pain, for instance, altered endogenous inhibition and decreased function of neurotransmitters [7, 26]

Inclusion criteria consisted of newly diagnosed, pathologically confirmed epithelial ovarian cancer, an age of 18 years or older, the ability to provide informed consent, willingness to provide access to medical records, undergoing interval or primary debulking surgery at UPMC/HCC, completing a full course (six cycles) of platinum-based chemotherapy at UPMC/HCC and willingness to provide biospecimens for banking purposes

Mc d nguyn nhn chnh xc ca n vn cha c bit, nhng n c cho l kt qu ca tn thng t bo i vi vng mc, do stress oxy ha Nghin cu v bnh mt lin quan n tui tc cho thy rng vic cho nhng ngi trn 50 tui b thoi ha th lc b sung cht chng oxy ha (bao gm beta-carotene) gip gim 25% nguy c pht trin bnh thoi ha im vng tin trin Tuy nhin, mt nh gi gn y ca Cochrane cho thy rng ch ring cht b sung beta-carotene s khng ngn nga hoc tr hon s suy gim th lc do AMD gy ra

In that regard, 3,3-dimethyl-1-butanol (DMB), a structural analog of choline has been found to inhibit microbial TMA lyase and reduced TMAO concentrations in mice fed with a choline or L-carnitine rich diet