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While this study suggests that in utero exposure may result in neurological effects, these results should be interpreted with caution, as the authors did not control for confounding variables, such as concomitant exposure to other neurotoxicants and nutritional deficiencies

The formulation strategy centers on trehalose and sucrose as primary cryoprotectants (typically 515% w/v), which form protective glass matrices around viral particles, preventing ice crystal formation and maintaining structural integrity during the freeze-drying process