glutathione and glutathione-s-transferase in detoxification mechanisms Homeostasis Functions: Potential Targets for Medical Interventions - Lushchak - 2012 - Journal of Amino Acids Glutathione-Mediated Conjugation of Anticancer Drugs:

While substantial research has focused on the molecular mechanisms conferring chemoresistance, our study highlights a distinct, underexplored phenomenon: ferroptosis-activating metabolites, particularly acrolein, can interfere with the efficacy of chemotherapeutics by inhibiting necroptosis

Decreased serotonin release and serotonergic fiber density are observed especially in the hippocampal region of 5xFAD mice (Tian et al., 2023), a feature also seen in depressive rats following intracerebroventricular injection of soluble A-42 (Colaianna et al., 2010)

A., Mignion, L., Desmet, C., Gourgue, F., Jonas, J

Free Radic Biol Med 9 : 235243 Sjostrom K, Crapo JD 1983 Structural and biochemical adaptive changes in rat lungs after exposure to hypoxia