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ROS/PI3K/Akt and Wnt/-catenin signalings activate HIF-1-induced metabolic reprogramming to impart 5-fluorouracil resistance in colorectal cancer

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In addition, two siblings also had spinocerebellar degeneration, peripheral neuropathy, myopathy and aminoaciduria [3, 8]

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The peptide is not approved by regulatory agencies such as the FDA or EMA for therapeutic use, and is currently available only for research purposes

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