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The sleep-timing rationale is dual-purposeendogenous GH release peaks during slow-wave sleep (stages 3 and 4), and MK-677's appetite-stimulating effects (a ghrelin mimetic side effect) are less disruptive when the subject is asleep

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655659 For example, a cell-free biosensing reaction layered over a custom chip with microelectrodes provided a ligand-dependent voltage readout

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