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Nature communications , 14 (1), 3372

The correlation analysis between molecular biomarkersspanning both gene and protein levelsand clinical outcomes, specifically intraocular pressure (IOP) reduction across different animals within the same treatment group was done to examine how the molecular expression patterns align with physiological responses

Lactulose is a non-absorbable carbohydrate administered enterally and is fermented by colonic bacteria to form organic acids, which lower the luminal pH