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Specifically, GPX4 utilizes GSH as a cofactor to detoxify lipid hydroperoxides, including polyunsaturated fatty acid hydroperoxides (PUFA-OOH), converting them into their corresponding alcohols (PUFA-OH)

Cell Stem Cell 14 , 306321 (2014)

PMID: 109 BarreraMJAguileraSCastroICarvajalPJaraDMolinaCet al

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