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doi:10.1111/jdv.16489

An isomeric mixture of 2- tert -butyl-4-methoxyphenol and 3- tert -butyl-4-hydroxyanisole (BHA), butylhydroxytoluene (BHT), and tert -butylhydroquinone (TBHQ) are chain-breaking ATs extensively used in the food industry as preservatives

An in vitro study carried out on a vincristine-resistant human colorectal carcinoma cell line had demonstrated that curcumin was not only toxic to the cancer cells in a dose-dependent manner, as the concentration started to rise from 25 M onwards, but also could reverse their sensitivity to drugs such as fluorouracil, vincristine, hydroxycamptothecin, and cisplatin [241]