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Functional studies include [ 14 C]-propionate or [ 14 C]- N 5 methyl-tetrahydrofolate incorporation into cellular macromolecules, to assess the activities of MCM and MS, respectively, and biosynthesis of MeCbl and AdoCbl upon metabolic labeling with holo-TC made from apo-TC and commercially available [ 57 Co]-vitamin B 12 (Watkins and Rosenblatt, 2013)

Food and Drug Administration (FDA) in 2021 for chronic weight management in adults and children 12 and older with obesity (BMI of 30 or more) and for adults who are overweight (BMI of 27 or more) with one or more weight-related health conditions, such as type 2 diabetes or high blood pressure

neonatal P59.1

Use restriction For laboratory research use only