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During titration, it is not recommended to increase by more than 2.5 mg every 4 weeks to avoid side effects

However, you should seek immediate medical attention if you experience signs of a serious reaction such as difficulty breathing, chest tightness, severe dizziness, rapid heartbeat, widespread rash, swelling of the face or throat, or severe injectionsite reactions like intense pain, significant swelling, or signs of infection (redness, warmth, pus, or fever)

For this reason, an overdose is very rare and it's generally considered safe, even at high doses

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