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Despite the important insights, this study has certain limitations

Researcher synthesised demethoxycurcumin and bis-demethoxycurcumin, in HERr2 + cells and MCF-7, the phytochemicals were discovered to limit cancer cell proliferation, as shown by an IC50 value below 10 M ( in vitro IC 50 concentrations may not directly reflect clinically achievable plasma or tissue levels, and translational interpretation requires pharmacokinetic validation

At least 40 mutations in the MTHFR gene have been identified in people with homocystinuria, a disorder in which the body is unable to process certain amino acids properly

Interstitial cystitis: a critique of current concepts with a new proposal for pathologic diagnosis and pathogenesis