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Rapid correction of acidosis with sodium bicarbonate in patients with diabetic ketoacidosis may cause hypokalemia, paradoxical acidosis in cerebrospinal fluid (CSF) since carbon dioxide diffuses more rapidly into CSF than does bicarbonate, and lactic acidosis since increased pH increases hemoglobin-oxygen affinity which, when combined with erythrocyte 2,3-diphosphoglycerate (2,3-DPG) deficiency in these patients, results in peripheral tissue hypoxia

[Google Scholar] 13.Wchtershuser G

Oral S-Adenosylmethionine in depression: A randomized, double-blind, placebo-controlled trial

Retatrutide targets metabolic receptors to help regulate insulin sensitivity and fat metabolism, commonly used in metabolic disorder research