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IL-1 has been shown to upregulate the expression of tyrosinase and tyrosine-related protein-1 (TRP1), potentially enhancing skin pigmentation by increasing melanin gene expression and promoting the production of additional inflammatory factors (Yang et al., 2022)

Furthermore, a subset of clinical investigations and animal trials have demonstrated that protracted recanalization therapy (lasting over 24 h or even approaching a month) confers benefits to patients, and the relevant mechanisms need further exploration [6, 7]

A GHK-Cu peptide serum might appear simple from a marketing perspective, but the reality is that it requires careful formulation balance, ingredient compatibility, and packaging stability to perform well in the hands of consumers

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