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The regular use of either proton-pump inhibitors (PPIs) or histamine H2 receptor antagonists (H 2 As) among these patients [5, 6] especially as an adjunct to aspirin therapy in the secondary prevention of cardiovascular events [17, 18] could also reduce the ability to digest B12 from food [19]

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Baseline data All participants were tested for vitamin B12, folate, haematological indices, iron studies, intestinal parasites and Helicobacter pylori stool antigen as part of the routine screening

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