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Additionally, it is essential to investigate the durability of their therapeutic effects and their ability to overcome resistance in HCC treatment

Furthermore, using the Illumina Infinium Human Methylation27 Bead Chip microarray, significant differences in methylation levels of CLDN16 , DDC , and NXT2 were observed in HD patients compared to controls (Zadel et al., 2018)

(2) Reconciling Actual and Estimated Costs of the Demonstration for Previous Years As described earlier, we have calculated the difference for FYs 2005 through 2017 between the actual costs of the demonstration, as determined from finalized cost reports once available, and estimated costs of the demonstration as identified in the applicable IPPS final rules for these years