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Description

The data were presented as the fold increase of the target gene expression, normalized to the housekeeping gene beta-actin, compared to unstimulated conditions

The therapeutic goal is to reduce free copper as early in the course of the disease as possible to prevent manifestation in the liver and brain

The isolated mRNA was reverse transcribed via the Superscript III First-Strand Synthesis System (ThermoFisher Scientific) according to manufacturers instructions

Brenner has been the recipient of multiple Top Doctors awards as well as published numerous publications, research articles and participated in a number of speaking engagements