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The treatment itself typically takes 30-60 minutes and is administered by a skilled professional

doi: 10.3390/molecules24234335

In addition, AS-IV-based SLN-gel can regulate collagen fiber arrangement and collagen deposition and reduce scar formation

Despite substantial treatment crossover and informative censoring, the COBALT RCT showed a non-statistically significant efficacy signal in favor of OCA treatment, and both the COBALT EC and HEROES trial emulation studies showed statistically significant superiority of OCA vs non-treatment