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Interestingly, older animals with higher body weights require increased intranasal dosages to reach the same drug concentration in the brain as in young animals

doi: 10.1016/j.ecl.2020.04.002 2 EzzatSAsaSLCouldwellWTBarrCEDodgeWEVanceMLet al

Establish administration route and dosing based on published pharmacokinetic data for the specific peptide

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