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10.1093/bja/aem131 168 WheelerS.Acord-ViraA

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Rhythmic transcripts that lost rhythmicity in cKOt mice (model 2) did not present clear phase enrichment but did show higher amplitudes (Figure 1, C and D), as expected for direct BMAL1 target genes in clock-deprived animals (27)

A total of 21 candidate COVID-19 inactivated vaccines have been approved for clinical trials as of March 28, 2022 ( COVID-19 live attenuated vaccines Live attenuated vaccines are based on the virus obtained by reverse genetics or adaptation to reduce virulence and are used as non-pathogenic or weakly pathogenic antigens