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Description

Current strategies can be broadly categorized into three approaches: (1) direct inhibition of HMGB1 to block its release or signaling via TLR4/RAGE

The application proposes a novel mechanism of action of the disclosed combination that stabilizes infected cells during viral infection resulting in higher cell survival in in- vitro demonstrations of the anti-viral effect of the present invention [Para 1 8] Oxidation stress occurs when the balance between the production and the disposal of reactive oxygen species (ROS) favors the production of excess ROS, also known as free radicals